Archuu Star Light Projector, 360 Degree Rotating 4 Modes 6 Movies 8 Songs Portable Birthday Night Light Projector,with 14 Keys Remote Control,Cartoon Toy Beamer Gift for Kids Babies

high discount SuHuYuHuJia Solar Paths Yards Porch Patio Yard for Light Solar Garden Decorative Metal Hanging Outdoor Sensor Light with Lantern Solar Lanterns Hanging Tools & Home Improvement

Author affiliations

high discount SuHuYuHuJia Solar Paths Yards Porch Patio Yard for Light Solar Garden Decorative Metal Hanging Outdoor Sensor Light with Lantern Solar Lanterns Hanging Tools & Home Improvement

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

high discount SuHuYuHuJia Solar Paths Yards Porch Patio Yard for Light Solar Garden Decorative Metal Hanging Outdoor Sensor Light with Lantern Solar Lanterns Hanging Tools & Home Improvement

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
FXZMJN Gold Metal Belly Waist Chain Tassel Sequins Charms Body Multilayer Chain Bikini Beach Turkish Dance Belt Jewelry (Color : Gold)

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the All Woman Super Wide Knee Highs 20 Denier 37" Stretch.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are WuLiangxi 1×5M(3.3×16.4ft) Stairs Safety Net - Children's Pet Balcony Railing Protection Net Indoor Playground Fence Nylon Isolation Net Retro Style Decorative Net Strong and Wear Resistant provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Pro Braking PBC0967-TRD-BLU Braided Clutch Line (Transparent Red Hose & Stainless Blue Banjos).

Read more about Emmanuela Comfortable Leather Flat Sandals with Metal Leaves, Quality Ancient Greek Style Dressy, Boho Chic Summer shoes, Split Toe Strappy Wedding Sandals, Ankle Strap.

Allied Brass MC-41-SM-30 Monte Carlo Collection 30 Inch Shower Door Towel Bar, Antique Copper

Social activity

Spotlight

Advertisements