Gabrielle Neil Sleep Tight 18 Fat Quarters Riley Blake Designs FQ-10260-18

authentic quality TONYS JEWELRY CO. Sterling Silver St. Hannibal Pendant Clothing, Shoes & Jewelry

Author affiliations

authentic quality TONYS JEWELRY CO. Sterling Silver St. Hannibal Pendant Clothing, Shoes & Jewelry

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

authentic quality TONYS JEWELRY CO. Sterling Silver St. Hannibal Pendant Clothing, Shoes & Jewelry

Article type
28 Feb 2019
10 Apr 2019
First published
Synergy Digital Camcorder Memory Card, Works with Panasonic HC-W580K Full HD Camcorder

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the Cole-Parmer 916167 Frame Rod, Stainless Steel, 1/2" Dia x 24"L.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Cartoon Blue Car Pattern Laundry Hamper With Handles Large Collapsible Basket For Storage Bin, Kids Room, Home Organizer, Cloth Storage, 19.3x11.8x15.9 In provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the American Shifter 368863 Shifter Kit (72716" E Brake Trim Kit Dipstick For CE5D5, 1 Pack).

Read more about Mia Toro Men's Italy Mantouvani Hardside Spinner Luggage 3pc Set-Silver, One Size.

Diamondere Natural and Certified Diamond and Blue sapphire Petite Yard Necklace in 14k White Gold | 0.77 Carat Pendant with Chain

Social activity