Bilstein 22-290403 Sport Car Shock Absorber

10 days return LAmade Kids Midnight-2T - (Toddler/Kid) Dress Christie Clothing, Shoes & Jewelry

Author affiliations

10 days return LAmade Kids Midnight-2T - (Toddler/Kid) Dress Christie Clothing, Shoes & Jewelry

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

10 days return LAmade Kids Midnight-2T - (Toddler/Kid) Dress Christie Clothing, Shoes & Jewelry

Article type
28 Feb 2019
10 Apr 2019
First published
WIONC Rattan Basket Dirty Clothes Basketry Desktop Storage Box Home Snack Case Willow Fabric Hoppet (Color : B, Size : 302012)

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the Wireless Backup Camera 5“ Split Screen System for RVs,Trailers,5th Wheels,Motorhomes,Truck Support 2 Rear View Camera inputs, 2.4G Stable Digital Signal Easy Installation YIMU WX5311S.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Liberty Blues Men's Big & Tall ™ Longer-Length Piqué Polo, Solids & Stripes - Big - 6XL, Black provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the BERRICLE Rhodium Plated Sterling Silver Cubic Zirconia CZ Wreath Open Circle Sun Fashion Dangle Drop Earrings.

Read more about IPCW EC-OK1302IA Front Replacement Engine Under Cover.

The North Face Eco Trail 3-Person Camping Tent

Social activity