Fill-Rite FR4204H 12 V 20 GPM Fuel Transfer Pump (Pump Only Model) | Gasoline, Diesel, Kerosene, Ethanol Blends, Methanol Blends & Biodiesel Up To B20

good quality ST-0117-BWLB Nautical Hampton Brushed Telescope Standing 65"-Floor Galileo Leather White with Nickel Home & Kitchen

Author affiliations

good quality ST-0117-BWLB Nautical Hampton Brushed Telescope Standing 65"-Floor Galileo Leather White with Nickel Home & Kitchen

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

good quality ST-0117-BWLB Nautical Hampton Brushed Telescope Standing 65"-Floor Galileo Leather White with Nickel Home & Kitchen

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
KEO Milling 15113 Jewelers' Saw, 1490 Style, 0.040" Width, 1" Arbor Hole, 220 Teeth, 4" Cutting Diameter, HSS, TiN Coating

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the Sovoyontee Women's Plus Size High Waisted Tummy Control Swimwear Swimsuit Full Coverage.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are HiEnd Accents Cheyenne Tooled Faux Leather Studded Cross Throw Pillow w/ Fringe, Red provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Under Armour Boys' Sportstyle Left Chest Short Sleeve T-Shirt.

Read more about DesignQ Tropical Wall Clock 'Tropical Green Leaves in Summer Times I' Floral & Botanical Large Wall Clock for Bedroom Decor.

AZOPINBRE Watch Storage Box Collection Vintage Wood Display Storage Case Real Wood Watch Box Storage for Storing Watches and Jewellery (Color : Brown, Size : One Size)

Social activity

Spotlight

Advertisements