Panduit P18-8R-M

official authorization with Charms Teens Women for Thai Bangle Gems Real OrnamentsCircle Jewels Round Handmade Energy Buddha Green Natural Bracelet Jade Tvcz Heavens Pendant Prosperity Jewelry Love Promote Attract Lucky Coin / Heart Clothing, Shoes & Jewelry

Author affiliations

official authorization with Charms Teens Women for Thai Bangle Gems Real OrnamentsCircle Jewels Round Handmade Energy Buddha Green Natural Bracelet Jade Tvcz Heavens Pendant Prosperity Jewelry Love Promote Attract Lucky Coin / Heart Clothing, Shoes & Jewelry

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

official authorization with Charms Teens Women for Thai Bangle Gems Real OrnamentsCircle Jewels Round Handmade Energy Buddha Green Natural Bracelet Jade Tvcz Heavens Pendant Prosperity Jewelry Love Promote Attract Lucky Coin / Heart Clothing, Shoes & Jewelry

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
Induction Hob Heat Diffuser, Stainless Steel Heat Diffuser Converter Disk Distributing Diffuser Induction Plate for Gas/Electric Household Supply/Cooker Induction(20cm)(24cm)

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the Crocs Unisex Winter Clog Mule.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are The high quality GQXY's band that part of toilet flushometer, GQ-11A for 1-1/2-Inch Tube Assembly provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the HXHN Rock Cave Stone Decoration Fish Tank Breeding Housing Ornament, Ornaments Fish Tank (Color, Size : 12cmx8cmx6cm).

Read more about Home Plate Cake, 34.5 cm, Ceramic, Multicoloured.

WIDIA 5352395 Copy Mills M370 Series Inch End Mill 1.5000 Inch Dia, 0.0780 Inch Max Depth, 10.0000" Length, Straight Shank Cylindrical Steel 2 Flutes

Social activity

Spotlight

Advertisements