2721402401, Intake Manifold Air Flap Runner Repair Kit Fit for Mercedes-Benz C230 C280 C300 C350 CLK350 E350 GLK350 GL45 ML350 R350 SLK280 SLK350 Models Engine

limited edition DESIGN HUB Girls or Women For Pendant)Jewelry (Only Chain WITHOUT Pendant Gemstone Silver Sterling 925 Solid Pendant Cts) (5 Larimar Cabochon Round Clothing, Shoes & Jewelry

Author affiliations

limited edition DESIGN HUB Girls or Women For Pendant)Jewelry (Only Chain WITHOUT Pendant Gemstone Silver Sterling 925 Solid Pendant Cts) (5 Larimar Cabochon Round Clothing, Shoes & Jewelry

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

limited edition DESIGN HUB Girls or Women For Pendant)Jewelry (Only Chain WITHOUT Pendant Gemstone Silver Sterling 925 Solid Pendant Cts) (5 Larimar Cabochon Round Clothing, Shoes & Jewelry

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
AMBF WE10S5TX1B-25 Standard String Wound Polypropylene Media 10 Micron, 2.5 Inch Filter Diameter 20 Inch Length, Tinned Steel Core, Open Ended/No Caps Buna O-Ring/Gasket (Pack 25)

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the Big Chill Boys' Colorblock Jacket.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Intermotor 39517 Fuel Pump High Pressure provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the MINGYAN Vacuum Sealer Bags for Comforters, Blankets, Bedding, Clothing Space Saver Bags with Hand Pump 80% More Storage Reusable (Color : 6 Pack Hand Pump Small).

Read more about Hypertech 120012 1990 S10/15 4.3 Tbi Auto W/Od Therm..

Millennium-Filters MN-HC8900FDN39Z Pall Hydraulic Filter, Direct Interchange

Social activity

Spotlight

Advertisements