6.25 Inch Polar Bears Cubs Playing Decorative Statue Figurine, White

low price & Woodworkers Manual Weavers Batik Pink R, Letter Monogrammed Standard, Sham, Pillow Home & Kitchen

Author affiliations

low price & Woodworkers Manual Weavers Batik Pink R, Letter Monogrammed Standard, Sham, Pillow Home & Kitchen

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

low price & Woodworkers Manual Weavers Batik Pink R, Letter Monogrammed Standard, Sham, Pillow Home & Kitchen

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
Rear Brake Rotors Drill Slot For 1975-1980 Granada, Versailles, Monarch

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the Mitsubishi Materials MHS0290L014B MHS Series Solid Carbide Drill, Internal Coolant, 2 mm Hole Depth, 2.9 mm Cutting Dia, 0.5 mm Point Length, 4 mm Shank Dia..

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are LDETXY Outer Clutch Cover for RZR XP 4 Turbo, Variator Clutch Housing Outer for 2018-2021 Polaris RZR XP Turbo S RS1 XP4 Accessories (Replace #2637068) provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Levi's® Big & Tall Men's Big & Tall 505® Regular Medium Stonewash Jeans 46 X 29.

Read more about Apple iPhone 12 Pro Max, 512GB, Gold - Unlocked (Renewed Premium).

Calvin Klein Performance Women's Shaggy Knit Full Zip Hoodie

Social activity

Spotlight

Advertisements