Schlage Commercial ND94BDRHO626 ND Series Grade 1 Cylindrical Lock, Classroom Vandlguard, Rhodes Lever Design, Satin Chrome Finish

sell like hot cakes Elevation Leg Restorology Pillow Discomfort Knee & Foot Swelling, Circulation, for Pillow Wedge Bed Supportive - Sleeping for Health & Household

Author affiliations

sell like hot cakes Elevation Leg Restorology Pillow Discomfort Knee & Foot Swelling, Circulation, for Pillow Wedge Bed Supportive - Sleeping for Health & Household

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

sell like hot cakes Elevation Leg Restorology Pillow Discomfort Knee & Foot Swelling, Circulation, for Pillow Wedge Bed Supportive - Sleeping for Health & Household

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
Scubapro MK19 Evo/D420 Regulator, DIN

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the TempoParis Reversible Jeans (Assorted Colors).

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Rare Parts RP19579 Sway Bar Link provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the HAOHANYU Watch Storage Box 12 Slots Wood Watch Display Boxes Case Luxury Watch and Jewelry Business Gift Case Brand Wooden Mechanical Watch Storage Box (Color : Brown).

Read more about Greenlee 36882 KNOCKOUT PUNCH, 28.3 mm.

Minka-Aire F855-DRF Wave 65" Ceiling Fan with Remote Control in Driftwood Finish

Social activity

Spotlight

Advertisements