AUUXVA Storage Bins Basket Rainbow Ballet Dancer Painting, Collapsible Storage Cube Ballerina Rectangle Storage Box with Handles for Shelf Closet Nursery Bedroom Home Office 2 Pack

fair prices 16 130240 Tolco oz. 150) of (Pack Red Thinner, Bottles, Cylinder Imprinted Industrial & Scientific

Author affiliations

fair prices 16 130240 Tolco oz. 150) of (Pack Red Thinner, Bottles, Cylinder Imprinted Industrial & Scientific

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

fair prices 16 130240 Tolco oz. 150) of (Pack Red Thinner, Bottles, Cylinder Imprinted Industrial & Scientific

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
PRP Seats B054-01 Rear Bench Cover for '16+ Toyota Tacoma Double Cab - Black with Red Stitching

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the TIDYON Dog Pool Large Foldable Collapsible Dog Pool Plastic Pool Portable Dog Swimming Pool Plastic Kiddie Pool for Kids Dogs in Summer (XXL 63").

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Knipex 97 71 180 Crimping Pliers for end sleeves 0,25-2,5mm with soft handle VDE-tested provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Billabong Men's Balance Crew Neck Sweatshirt.

Read more about Dormer C42825.0 Shank Roughing End Mill, ALCRONA Coating, Cobalt High Speed Steel PM, 25 mm Head Diameter, 45 mm Flute Length.

TONYS JEWELRY CO. Sterling Silver St. Nathanael Pendant

Social activity

Spotlight

Advertisements