CGSignLab 2455156_5gfxw_27x18_None New Year's Sale, Ghost Aged Brick Repositionable Opaque White 1st Surface Static, Cling Non, Adhesive Window Decal, Vinyl, 27" x 18" (Pack of 5)

high quaity Roll Tape Film Polyester ft. 180 x in. 0.75 – Tape Transfer Adhesive 9495MP 3M with Tapes Sealing and Bonding Resistance. Solvent Strength, Shear Industrial & Scientific

Author affiliations

high quaity Roll Tape Film Polyester ft. 180 x in. 0.75 – Tape Transfer Adhesive 9495MP 3M with Tapes Sealing and Bonding Resistance. Solvent Strength, Shear Industrial & Scientific

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

high quaity Roll Tape Film Polyester ft. 180 x in. 0.75 – Tape Transfer Adhesive 9495MP 3M with Tapes Sealing and Bonding Resistance. Solvent Strength, Shear Industrial & Scientific

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
Raybestos BC94039 Professional Grade Parking Brake Cable

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the DERCLIVE Knee Elbow Pads with Wrist Guards Protective Gear for Outdoor Skateboarding Bike Cycling.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Millennium-Filters MN-SE125H03B STAUFF Hydraulic Filter, Direct Interchange, Silver provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Chicken Funny Dishwasher Magnet for Front Door Cover,Country Rooster Hen Dishwasher Decal Decoration,Farmhouse Fridge Magnetic Panel Refrigerator Skins Decorative Appliance Sticker 23"x26".

Read more about Spin Mop with Self Separate Clean and Dirty Water System,with 3 Washable and Reusable Pad, Suitable for Hardwood, Wood, Laminate, Tile, Ideal for Pet Owners (Off White).

LED Full Length Mirror Wall Mounted Lighted Floor Mirror Dressing Mirror Make Up Mirror Dimmer Touch Switch,for Bathroom/Bedroom/Living Room/Dining Room/Entry

Social activity

Spotlight

Advertisements