Wireless Charger, 3 in 1 Fast Wireless Charging Station, 18W Wireless Charging Stand Dock Foldable for Apple Watch SE/7/6/5/4/3/2 AirPods 3/2/Pro iPhone 13/12/11/Pro/XS/Xs Max/XR/X/SE/8/8 Plus

best-selling Roundhill Furniture Lenola Accent Armchair, one Chair, Gray Home & Kitchen :

Author affiliations

best-selling Roundhill Furniture Lenola Accent Armchair, one Chair, Gray Home & Kitchen :

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

best-selling Roundhill Furniture Lenola Accent Armchair, one Chair, Gray Home & Kitchen :

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
Amarelo Womens Butt Lift, Skinny, high Waist Colombian Original Jeans - Levanta Cola Colombiano para Mujer (Ice Blue, 1)

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the Linqin Thanksgiving Seamless Pattern Storage Bin Collapsible with Handle Rectangle Waterproof Basket for Storage Cube Closet Organizer for Toy Nursery Book Office Shelf Bathroom.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Sisha-A Winter Warm Authentic Australia Sheepskin Car Seat Cover Luxury Long Wool Front Seat Cover Fits Most Car, Truck, SUV, or Van (Grey Tips) provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Navaris Wood Monitor Stand Riser - Computer Desk Organizer Desktop Dock Wooden Mount Display for PC TV Screen Notebook Laptop - Walnut.

Read more about Killer Filter Replacement for EPPENSTEINER 960LAH10XLF000P.

Power Stop KC3109 Z23 Evolution Sport Performance 1-Click Brake Kit with Caliper

Social activity

Spotlight

Advertisements