WFLNHB Shift Cable Kit Replacement for OMC Cobra Sterndrive Replace for 987661 986654 987498

best-selling mm 6 Nose, Ball Mill, End Material Hard HP 7050 Plus Vision 705006004RT Hanita WIDIA Cutting 4-Flute Shank, Straight Cut, RH TiAlN, Carbide, Dia, Industrial & Scientific

Author affiliations

best-selling mm 6 Nose, Ball Mill, End Material Hard HP 7050 Plus Vision 705006004RT Hanita WIDIA Cutting 4-Flute Shank, Straight Cut, RH TiAlN, Carbide, Dia, Industrial & Scientific

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

best-selling mm 6 Nose, Ball Mill, End Material Hard HP 7050 Plus Vision 705006004RT Hanita WIDIA Cutting 4-Flute Shank, Straight Cut, RH TiAlN, Carbide, Dia, Industrial & Scientific

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
Seco 36693 PerfoMAX Indexable Insert Drill, 1.26" Diameter, 3.2677" Tool Flute Length, 1.1024" Shank Diameter, Modular Connection Shank

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the MACHEREY-NAGEL 726215.25 Optima 5 MS Capillary Columns for GC, Film Thickness: 0.35 µm, Length: 25 m, 0.2 mm ID, USP: G27, G36.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are 3dRose CST_57236_3 Joyeux Noel Merry Christmas in French Eiffel Tower Ceramic Tile Coasters, Set of 4 provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Nostalgic Warehouse 733353 Meadows S Grip Entry Set, Backset - 2.375", Satin Nickel.

Read more about Men's 100% Silk Blue Patriotic Pledge of Allegiance American Flag Necktie Tie.

Trash Can with Lid Seamless with Rose Golden Deer Antlers Nature Animal Backdrop in Pink Press Cover Small Garbage Bin Round with Wooden Legs Waste Basket for Bathroom Kitchen Bedroom 7L/1.8 Gallon

Social activity

Spotlight

Advertisements