Eagle Eyes FR464-U000R Passenger Side Taillamp Assy Fits Mercury Grand Marquis

are doing discount activities North by 20) of (Pack Green Standard, w/Suspension, Hat Hard Series Peak A79R040000 Honeywell Tools & Home Improvement

Author affiliations

are doing discount activities North by 20) of (Pack Green Standard, w/Suspension, Hat Hard Series Peak A79R040000 Honeywell Tools & Home Improvement

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

are doing discount activities North by 20) of (Pack Green Standard, w/Suspension, Hat Hard Series Peak A79R040000 Honeywell Tools & Home Improvement

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
KSport CDG02-GR Rally Spec GR Damper System

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the Smartwool Kids' Merino 250 Baselayer Pattern Bottom.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Stupell Industries Blue Gear Shape Abstraction Layered Opaque Details, Designed by Grace Popp Canvas Wall Art, 16 x 20 provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the D&D PowerDrive 25N9500J5 Metric Standard Replacement Belt, Rubber.

Read more about Kipp 03035-2A6 Stainless Steel Spring Plungers, Ball Style, Hexagon Socket, Heavy End Pressure, Inch, 5/8-11 Thread (Pack of 5).

Wall Shelves, 80x9x3 cm Wall Mounted Shelf for Family for Books

Social activity

Spotlight

Advertisements