COEQINE Red Rose Print Women Car Seat Cushion Pad for Car Driver Seat Office Chair Home Use, Soft and Breathable Seat Cushion

cheap and fashion Sunshade Zone AutoTech for Shade Sun Windshield Custom-fit Coupe, Civic Honda 2016-2022 Automotive

Author affiliations

cheap and fashion Sunshade Zone AutoTech for Shade Sun Windshield Custom-fit Coupe, Civic Honda 2016-2022 Automotive

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

cheap and fashion Sunshade Zone AutoTech for Shade Sun Windshield Custom-fit Coupe, Civic Honda 2016-2022 Automotive

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
Dell XPS 13 9310 13.4" Ultra HD+ (3840 x 2400) Touchscreen Laptop - 11th Gen Intel Core i7-1185G7 up to 4.80 GHz CPU, 16GB LPDDR4x RAM, 1TB SSD, Intel Iris Xe Graphics, Windows 10 Home

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the DNA MOTORING LP-GM1068185 Front License Plate Mounting Bracket Compatible with Chevy Trax 2017-2021, Matte Black.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are 3dRose " Border Collie Dog Dad Doggie by Breed Brown Muddy Paw Prints Love Doggy Lover Pet Owner" Travel Mug, 14 oz, Multicolor provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the WIDIA Hanita 7N2201831RJ Vision Plus Micro 7N22 HP Hard Material End Mill, 1.8 mm Cutting Diameter, Carbide, TiAlN, RH Cut, Straight Shank, 2-Flute.

Read more about Hazet 6290-1CTCAL Torque wrench DAkkS 9x12, 5-60 Nm.

Gocase Cherry Petals Cherry Blossom Case Compatible with iPhone 6 Plus / 6S Plus Transparent with Print Silicone Transparent TPU Protective Case Scratch-Resistant Mobile Phone Case

Social activity

Spotlight

Advertisements