Switching LED Driver Power Supply - Cable for Input and Output, 48V 6700mA 321W

fast shipping AURELIOR Tropical Packs) Decor(12 Home Hardware Cabinet Drawers Dresser Cabinets Kitchen for Pulls Drawer and Handles Cabinet Pull, Handle Green Pattern Leaf Tools & Home Improvement

Author affiliations

fast shipping AURELIOR Tropical Packs) Decor(12 Home Hardware Cabinet Drawers Dresser Cabinets Kitchen for Pulls Drawer and Handles Cabinet Pull, Handle Green Pattern Leaf Tools & Home Improvement

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

fast shipping AURELIOR Tropical Packs) Decor(12 Home Hardware Cabinet Drawers Dresser Cabinets Kitchen for Pulls Drawer and Handles Cabinet Pull, Handle Green Pattern Leaf Tools & Home Improvement

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
Manual Woodworkers & Weavers Fabric Shower Curtain, White Sketched Ikat

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the ARP 114-3605 Cylinder Head Bolt Kit.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are SYMMCO SP-5-6x8 Plate Stock, 841 Sintered Bronze Oil Impregnated, 5.00" x 6.00" x 0.500" Thick provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Navy Blue Oversized Queen Size Striped Duvet Covers Set with Zipper & Corner Ties,600 Thread Count Soft Simple Style 100% Natural Cotton Farmhouse Duvet Bedding Sets(1 Quilt Cover+2 Pillowshams).

Read more about Women's Handbags Leather Shoulder Bags Stylish Hobo Bags Large Wallets and Totes with Adjustable Straps.

PonyCycle Authentic Unicorn Ride on Toy Mechanical Unicorn (with Brake/ 30" Height/ Size 3 for Age 3-5 ) White Ride on Unicorn Giddy up Ride Horse Plush Ux304

Social activity

Spotlight

Advertisements