LeCalla Links Sterling Silver Italian Paperclip Chain Necklace for Teen Women and Men (18, 20, 24, 36 Inches)

more discount Mob Direct VESA 75mm Armor Electronics

Author affiliations

more discount Mob Direct VESA 75mm Armor Electronics

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

more discount Mob Direct VESA 75mm Armor Electronics

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
Mugen Monster Hunter Custom Gaming Keycaps for Cherry MX Switches - Fits Most Mechanical Keyboards - with Keycap Puller

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the Cambridge Audio DacMagic 100 S/PDIF Digital to Analog Converter DAC with Toslink Input, TV Compatible, 192kHz (Silver).

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Metal Gear Survive - PS4 provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Auxbeam H4 RGB LED Light Kits, F-B5 Series LED HB2/ 9003 LED Daytime Running Light, Mobile APP Bluetooth Control, 60W 15000 Lumens Upgrade CSP Chips Replace Halogen Bulbs, Pack of 2.

Read more about 1Pc 3 Slots Portable Watch Box Round Watch Organizer Elastic PU Watch Case Leather 3-Digit Watch Storage Box.

HELLOFISH Wooden Jigsaw Puzzles for Adults - Unique Laser Cut Wood Puzzles, Jupiter Galaxy Puzzle Great as Gifts and Family Games - 8.6in x 0.2in 210 Piece

Social activity

Spotlight

Advertisements