American Shifter 362173 Shifter Kit (904 12" E Brake Trim Kit Dipstick For CCBC5, 1 Pack)

cheap wholesale Phone- 64GB S8 Galaxy Samsung 5.8" (Renewed) Black Midnight - Unlocked Verizon display, Cell Phones & Accessories

Author affiliations

cheap wholesale Phone- 64GB S8 Galaxy Samsung 5.8" (Renewed) Black Midnight - Unlocked Verizon display, Cell Phones & Accessories

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

cheap wholesale Phone- 64GB S8 Galaxy Samsung 5.8" (Renewed) Black Midnight - Unlocked Verizon display, Cell Phones & Accessories

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
Steve Madden Women's Flossi Slipper

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the CELLTREAT Scientific Products 229512 12-Well Cell Culture Plate with Lid; 100/cs.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Flash Furniture Dark Gray Mobile Desk Chair with 360 Degree Tablet Rotation and Under Seat Storage Cubby provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the AMBF WN20S1EX8V-30 Std. String Wound Natural Cotton Media 20 Micron, 2.5 Inch Filter Dia. 9.875 Inch Length, Polypropylene Core, Single Open End/Spring End Cap Viton O-Ring/Gasket (Pack of 30).

Read more about Wall Mounted Coat Rack, Entrance Hanger Wall Coat Rack Wall Coat Rac European Style Wall Coat Hook Entrance Storage Rack Bedroom Office Entry Coat Rack for Coats, Scarves, Bags, Towels, Keys, Hats.

Nostalgic Warehouse 765171 Victorian Plate with Keyhole Non-Handed Swan Lever Privacy, Backset Size: 2.75", Satin Nickel

Social activity

Spotlight

Advertisements