Stupell Industries Red Stripe Lighthouse Rocky Beach Coast Sailboat Waters Grey Framed Wall Art, 20 x 16, Blue

hot Storage Screws with Shelf Bathroom Mounted Wall Caddy Shower Corner Brackets Rod and Shelf 2pcs ULTNICE Organizer Black Kitchen and Dorm Toilet for Home & Kitchen :

Author affiliations

hot Storage Screws with Shelf Bathroom Mounted Wall Caddy Shower Corner Brackets Rod and Shelf 2pcs ULTNICE Organizer Black Kitchen and Dorm Toilet for Home & Kitchen :

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

hot Storage Screws with Shelf Bathroom Mounted Wall Caddy Shower Corner Brackets Rod and Shelf 2pcs ULTNICE Organizer Black Kitchen and Dorm Toilet for Home & Kitchen :

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
Walter Prototyp - Perform Tap TC216-M16X1.5-L0-WY80FC

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the Wintec Compatible TLPLW13 Replacement lamp for Toshiba TDP-T350, TDP-TW350 Projector.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Steve Madden Mens Lifted Velvet Padded Insle Smoking Loafers provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Sandvik Coromant 1P230-0900-XB 1630 CoroMill Plura Solid Carbide Square Shoulder End Mill, 0.3543" Cutting Diameter, 0.6496" Depth of Cut, 2.8346" Length, 10 mm Shank, Weldon 10 mm (Pack of 1).

Read more about SSWBasics White Round Rack KD.

KMP Creative Lifestyle Products 1417670401 Case for Apple iPhone x Manhattan Black

Social activity

Spotlight

Advertisements