Innes Writing Desk, Drawer Interior: 2.95'''' H x 21.81'''' W x 16.54'''' D, Finished Back: Yes

the best selection of Pants Pack 2 JOYBOS Hangers Lid with Boxes Storage Fabric Linen Foldable Lids with Bins Storage & Saving Space Home & Kitchen

Author affiliations

the best selection of Pants Pack 2 JOYBOS Hangers Lid with Boxes Storage Fabric Linen Foldable Lids with Bins Storage & Saving Space Home & Kitchen

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

the best selection of Pants Pack 2 JOYBOS Hangers Lid with Boxes Storage Fabric Linen Foldable Lids with Bins Storage & Saving Space Home & Kitchen

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
ACDelco Professional TC359 Inline to Trailer Wiring Harness Connector

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the Moen T3113ORB Kingsley Moentrol Volume Control Tub Shower Trim Kit, Valve Required, Oil Rubbed Bronze.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Besnfoto Low Profile Camera Ball Head CNC Metal Tripod Head Heavy Duty with Pan Lock, 1/4" Quick Release Plate for DSLR Camera Vertical Horizontal Level Bubble Arca/RRS Compatible Max Load 48lbs/22kg provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Mr. Jack (Revised Edition).

Read more about Stupell Industries Cute Boxer Dog Pet Portrait Minimal Brown, Design by George Dyachenko Black Framed Wall Art, 24 x 30.

Nintendo Animal Crossing Amiibo Cards - Series 1, 2, 3, 4 and 5 - 5 Pack - 15 Cards Total

Social activity

Spotlight

Advertisements