Linqin Autumn Orange Pumpkins Storage Bin Collapsible with Handle Rectangle Waterproof Basket for Storage Cube Closet Organizer for Toy Nursery Book Office Shelf Bathroom

authentic online Decoration Swing Outdoor Playground Netting Trailer Cargo Truck Rope Woven Climbing Fence Safety Protection Children QINLMITE (Size 33ft)) * 10m(7 * 2 : Baby Products

Author affiliations

authentic online Decoration Swing Outdoor Playground Netting Trailer Cargo Truck Rope Woven Climbing Fence Safety Protection Children QINLMITE (Size 33ft)) * 10m(7 * 2 : Baby Products

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

authentic online Decoration Swing Outdoor Playground Netting Trailer Cargo Truck Rope Woven Climbing Fence Safety Protection Children QINLMITE (Size 33ft)) * 10m(7 * 2 : Baby Products

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
NTK 24248 Oxygen Sensor

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the FIA SL67-67 RED Custom Fit Front Seat Cover Bucket Seats - Leatherette (Black w/Red Center Panel).

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are IGI Certified Natural Diamond Square Design Pendant In 18K BIS Hallmarked Stamped Fine Rose Gold 100% Certified Jewelry Available In Major Diamond Color-Clarity Range provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Leviton VerifEye Series 3500 Modbus TCP/BACnet IP Indoor Meter Kit with 3 Split Core CT's, 800-Amp, 3KUMT-8M.

Read more about Shoulder Bag Grey Pink Flamingo Messenger Bag Leather Satchel Bags For Women.

Power Rangers Dino Fury 5 Ranger Team Multipack 6-Inch Action Figure Toys with Dino Fury Keys and Chromafury Saber Weapon Accessories (Amazon Exclusive)

Social activity

Spotlight

Advertisements