AMBF WS75S2TX9T-50 Standard String Wound Polypropylene FDA Media 75 Micron, 2.5 Inch Filter Diameter 9.75 Inch Length, Tinned Steel Core, Double Open end Gasket Teflon O-Ring/Gasket (Pack of 50)

sale online DIEDERICHS 6526825 Mirror Complete Left Automotive

Author affiliations

sale online DIEDERICHS 6526825 Mirror Complete Left Automotive

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

sale online DIEDERICHS 6526825 Mirror Complete Left Automotive

Article type
28 Feb 2019
10 Apr 2019
First published
D&D PowerDrive 680-8M-434 Synchronous Timing Belt, Rubber, (Pack of 1)

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the Solid 14k Gold Linear Cross INRI Crucifix Pendant Necklace.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are SMARTOP 18"x12" Self Healing 3 Layer Folding Cutting Mat, Non-Slip Non-Reflective, Great for Crafts, Quilting, Sewing, Scrapbooking Molandi Yellow (Molandi Yellow) provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the DesignQ Lake House Wall Clock 'Haystacks On Orange Fields I' Landscape & Nature Large Wall Clock for Office Decor.

Read more about ALBBMY Wine Glass Rack Under Cabinet Decorative Hanging Wine Glass Holder (Color : 15035(Highly Customized)).

La Pastiche Houses on The Achterzaan with Gold Pearl Framed Oil Painting, 30" x 26", Multi-Color

Social activity