Orbus 4WX10H-G-OB18 4 x 10 ft. Scrim Single Sided Hanging Banner

cheapest price Hammock Playground Net Protective Balcony Stair Net Fence Railings Pets Netting, Safety Climbing Children QINLMITE Anti-Fall 20ft)) * 6m(13 * 4 : (Size Net Baby Products

Author affiliations

cheapest price Hammock Playground Net Protective Balcony Stair Net Fence Railings Pets Netting, Safety Climbing Children QINLMITE Anti-Fall 20ft)) * 6m(13 * 4 : (Size Net Baby Products

In the mucosal epithelium, the cellular glycocalyx can project tens to hundreds of nanometers into the extracellular space, erecting a physical barrier that provides protective functions, mediates the exchange of nutrients and regulates cellular interactions. Little is understood about how the physical properties of the mucosal glycocalyx influence molecular recognition at the cellular boundary. Here, we report the synthesis of PEG-based glycopolymers with tunable glycan composition, which approximate the extended architecture of mucin glycoproteins, and tether them to the plasma membranes of red blood cells (RBC) to construct an artificial mucin brush-like glycocalyx. We evaluated the association of two lectins, ConA and SNA, with their endogenous glycan ligands on the surface of the remodelled cells. The extended glycocalyx provided protection against agglutination of RBCs by both lectins; however, the rate and magnitude of ConA binding were attenuated to a greater degree in the presence of the glycopolymer spectators compared to those measured for SNA. The different sensitivity of ConA and SNA to glycocalyx crowding likely arises from the distinct presentation of their mannoside and sialoside receptors, respectively, within the native RBC glycocalyx.

cheapest price Hammock Playground Net Protective Balcony Stair Net Fence Railings Pets Netting, Safety Climbing Children QINLMITE Anti-Fall 20ft)) * 6m(13 * 4 : (Size Net Baby Products

Article type
Paper
Submitted
28 Feb 2019
Accepted
10 Apr 2019
First published
Over the Door Hook Hanger, Organizer Rack Dhcsf Wall-Mounted Coat Rack Coat Hook Entrance Key Coat Hook Nordic Creative Tea Mirror Hook Hanger (Size : B)

Faraday Discuss., 2019,219, 138-153

Engineering of spectator glycocalyx structures to evaluate molecular interactions at crowded cellular boundaries

D. J. Honigfort, M. H. Zhang, S. Verespy and K. Godula, Faraday Discuss., 2019, 219, 138 DOI: 10.1039/C9FD00024K

To request permission to reproduce material from this article, please go to the D&D PowerDrive 1248-8M-299 Synchronous Timing Belt, Rubber, (Pack of 1).

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are Melrose 9" Battery Operated LED Flameless Candle Outdoor Lawn Stake Luminary with Bird Motif provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Sandvik Coromant, C8-CPA-01, Cover (Pack of 1).

Read more about Bebe Bask - - Handmade Baby Doll Bed - - 100% Natural Organic Rattan with Luxury Cotton Mattress - - L17 x W11 x H7.5 Inches - - Comes Readymade with Beautiful Drawstring Cotton Bag.

Monoprice Blackbird 4K 4x1 HDMI 1.4 Switch - Quad Multiview, HDCP 2.2, Includes IR Remote, 1080P 60Hz, 10.2 Gbps, 5 Display Modes (Compatible with PS4/5 Xbox Apple TV Fire Stick Roku Blu-Ray Player)

Social activity

Spotlight

Advertisements